abstract：:Polycarbonate (PC) substrate is well suited for culturing human mesenchymal stem cells (MSCs) with high proliferation rate, low cell apoptosis rate and negligible cytotoxic effects. However, little is known about the influence of PC on MSC activity including senescence, differentiation and secretion. In this study, th...

journal_title：Clinical hemorheology and microcirculation

authors： Zou J,Wang W,Kratz K,Xu X,Nie Y,Ma N,Lendlein A

更新日期：2018-01-01 00:00:00

abstract：AIM:To investigate three-year outcomes of patients presenting with nonSTelevation acute coronary syndrome (NSTE-ACS) treated with bioresorbable everolimus-eluting vascular scaffolds (BRS). METHODS AND RESULTS:The study included a total of 488 consecutive patients, enrolled between May 2012 and December 2013 (median ag...

journal_title：Clinical hemorheology and microcirculation

authors： Anadol R,Dimitriadis Z,Polimeni A,Wendling F,Gönner S,Ullrich H,Lorenz L,Weissner M,Munzel T,Gori T

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Despite of the more potent immunosuppressive medication, vascular rejection is still a major issue after renal transplantation. Renal biopsy is the gold standard diagnostic to evaluate acute and chronic allograft rejection. As it is an invasive diagnostic there is the risk of complications like haematoma, ar...

journal_title：Clinical hemorheology and microcirculation

authors： Mueller-Peltzer K,Negrão de Figueiredo G,Fischereder M,Habicht A,Rübenthaler J,Clevert DA

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:To assess the severity of renal pathology in patients with chronic kidney disease (CKD) using contrast-enhanced ultrasonography (US). METHODS:275 patients with CKD who were proven by renal biopsy and 30 healthy adults were examined using conventional US and contrast-enhanced US. Ultrasonic parameters include...

journal_title：Clinical hemorheology and microcirculation

authors： Yang WQ,Mou S,Xu Y,Xu L,Li FH,Li HL

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Haemochromatosis is an iron-storage disease with different genetic mutations, characterized by an increased intestinal absorption of iron, resulting in a deposition of excessive amounts of iron in parenchymal cells. When the iron is released in the blood, it is left in an unliganded form, where it can partic...

journal_title：Clinical hemorheology and microcirculation

authors： du Plooy JN,Bester J,Pretorius E

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Cardiac surgery with cardiopulmonary bypass is associated with important changes in the microcirculation, usually attributed to endothelial dysfunction. Another common finding of cardiac surgery is postoperative thrombocytopenia and platelet loss of function. OBJECTIVE:To investigate the association between...

journal_title：Clinical hemorheology and microcirculation

authors： Di Dedda U,Ranucci M,Porta A,Bari V,Ascari A,Fantinato A,Baryshnikova E,Cotza M

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Patients having coronary artery disease treated by coronary bypass or PCI procedure are exposed to tissue damage because of the phenomenon called reperfusion injury. Reperfusion injury can be characterized/monitored by oxidative stress parameters, inflammatory markers and by post-operative complication rate....

journal_title：Clinical hemorheology and microcirculation

authors： Pintér Ö,Hardi P,Nagy T,Gasz B,Kovács V,Arató E,Sínay L,Lénárd L,Jancsó G

更新日期：2017-01-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) are targeted as vehicles for cell mediated gene therapy. Here we report on a macromolecular carrier, which was designed aiming at successful targeted gene delivery into MSCs through the mediation of folate receptor and reduced cytotoxicity compared to established cationic polymer vector -...

journal_title：Clinical hemorheology and microcirculation

authors： Wang W,Li W,Wang J,Hu Q,Balk M,Bieback K,Stamm C,Jung F,Tang G,Lendlein A,Ma N

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To identify the indications for CEUS in renal imaging in an interdisciplinary ultrasound department. METHODS:102 CEUS examinations of the kidney in 82 patients between September 2014 and July 2016 were analysed regarding the indication for ultrasound. CEUS was performed by one experienced sonographer agent a...

journal_title：Clinical hemorheology and microcirculation

authors： Putz FJ,Erlmeier A,Wiesinger I,Verloh N,Stroszczynski C,Banas B,Jung EM

更新日期：2017-01-01 00:00:00

abstract：:The study aimed to investigate local thermally induced microvascular reactivity in patients with type 1 (T1DM) or type 2 diabetes mellitus (T2DM) and polyneuropathy and to compare it with healthy controls. A hundred and fourteen subjects were investigated divided into 3 groups: 1st group -20 patients with T1DM; 2nd gr...

journal_title：Clinical hemorheology and microcirculation

authors： Stoyneva Z,Velcheva I,Antonova N,Titianova E

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:The interleukin-1 receptor antagonist (IL-1RA) contributes to tumor survival and progression in multiple cancer entities. IL-1RA polymorphisms influence IL-1RA expression patterns and function. A known polymorphism was correlated with clinical outcomes in melanoma patients with particularly aggressive disease...

journal_title：Clinical hemorheology and microcirculation

authors： Broer PN,Aung T,Heidekrueger PI,Prantl L,Narayan D

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:To evaluate the combination of conventional ultrasound (US) and acoustic radiation force impulse (ARFI) elastography in predicting triple-negative breast cancer and the likelihood of lymphatic metastasis. MATERIALS AND METHODS:A total of 178 women presenting from May 2013 to September 2015 with pathologically ...

journal_title：Clinical hemorheology and microcirculation

authors： Pu H,Zhao LX,Yao MH,Xu G,Liu H,Xu HX,Wu R

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:It is difficult to assess tumors of the parotid gland preoperatively. However, it is essential for the surgeon to know which kind of tumor is present. Ultrasound is the method of choice, but there is still no reliable differential diagnostic tool for determining whether a tumor is malignant or benign. OBJEC...

journal_title：Clinical hemorheology and microcirculation

authors： Zengel P,Notter F,Reichel CA,Clevert DA

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:Urea transporter-B (UT-B), highly expressed in erythrocyte, confers specific permeability to urea, urea analogues and water. The purpose of this study was to determine the hemorheological properties of UT-B null erythrocyte using a series of biophysical techniques. METHODS AND RESULTS:The blood was taken fro...

journal_title：Clinical hemorheology and microcirculation

authors： Geng X,Lei T,Zhou H,Yao W,Xin W,Yang B

更新日期：2017-01-01 00:00:00

abstract：:The radial dispersion of red blood cells (RBCs) near the vessel wall can significantly affect the transport dynamics in small vessels. The radial dispersion of RBCs is mainly caused by collisions between RBCs and this can be enhanced by aggregation. The objective of this study is to numerically investigate on the effe...

journal_title：Clinical hemorheology and microcirculation

authors： Ju M,Leo HL,Kim S

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Tetrahydrobiopterin (BH4), an endogenous nucleic acid derivative, acts as an important cofactor for several enzymes found within the vascular endothelium, which is deranged in sepsis. OBJECTIVE:We hypothesized that BH4 would improve capillary density and decrease inflammation within the intestinal microcirc...

journal_title：Clinical hemorheology and microcirculation

authors： Dumbarton TC,Maxan A,Farah N,Sharawy N,Zhou J,Nantais J,Lehmann C

更新日期：2017-01-01 00:00:00

abstract：:At present there is no widely accepted biomarker for monitoring of vascular functions. The purpose of this prospective study was to investigate the association of some blood biomarkers with vascular reactivity in patients with peripheral arterial diseases (PAD). A prospective evaluation was made of 3 groups comprising...

journal_title：Clinical hemorheology and microcirculation

authors： Akkoca M,Usanmaz SE,Koksoy C,Bengisun U,Demirel-Yilmaz E

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Reduced availability of nitric oxide leads to dysfunction of endothelium which plays an important role in the development of cardiovascular diseases. OBJECTIVE:The aim of the present study was to determine whether the dietary supplement L-arginine improves the endothelial function of microvessels by increas...

journal_title：Clinical hemorheology and microcirculation

authors： Melik Z,Zaletel P,Virtic T,Cankar K

更新日期：2017-01-01 00:00:00

abstract：:Anemia in pregnant women is associated with increased maternal and perinatal mortality and represents an important economic burden in many developing countries. Our goal was to evaluate the impact of anemia on the capillary network during pregnancy. Therefore, we compared microcirculatory parameters of anemic pregnant...

journal_title：Clinical hemorheology and microcirculation

authors： Sharawy N,Hussein A,Hossny O,Refaa A,Saka A,Mukhtar A,Whynot S,George R,Lehmann C

更新日期：2016-11-25 00:00:00

abstract：OBJECTIVES:Although the microcirculatory dysfunctions of edema formation are well documented, the draining pattern of dermal edema lacks information. This study was to assess the potential drainage pathways of the interstitial fluid in patients with ankle edema using the anatomical and histological methods. METHODS AN...

journal_title：Clinical hemorheology and microcirculation

authors： Li H,Yang C,Lu K,Zhang L,Yang J,Wang F,Liu D,Cui D,Sun M,Pang J,Dai L,Han D,Liao F

更新日期：2016-10-05 00:00:00

abstract：BACKGROUND:Cigarette smoking deteriorates human health via vascular disorders, cancer and especially respiratory diseases. The aim of this study is to investigate effects of cigarette smoking on hemorheologic parameters, plasma osmolality and lung function in individuals without diagnosis of chronic obstructive pulmona...

journal_title：Clinical hemorheology and microcirculation

authors： Ergun DD,Karis D,Alkan FA,Cakmak G,Yenigun M,Ercan M

更新日期：2016-10-05 00:00:00

abstract：UNLABELLED:Revascularization after long term aortic ischaemia in vascular surgery induces reperfusion injury accompanied with oxidative stress and inflammatory responses. The hypothesis of this study was that the aortic occlusion followed by controlled reperfusion (CR) can reduce the ischaemia-reperfusion injury, the s...

journal_title：Clinical hemorheology and microcirculation

authors： Jancsó G,Arató E,Hardi P,Nagy T,Pintér Ö,Fazekas G,Gasz B,Takacs I,Menyhei G,Kollar L,Sínay L

更新日期：2016-09-12 00:00:00

abstract：:The lecture was presented during the Fåhraeus award ceremony for 2016 at the University of Lisbon. It summarizes the main results and some of the more important hemorheological contributions achieved in the Laboratory of Biodynamics and Biorheology of the Institute of Mechanics to BAS and in collaboration with other l...

journal_title：Clinical hemorheology and microcirculation

authors： Antonova N

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:To investigate the difference of standard values of Supersonic shear imaging (SSI) and Acoustic Radiation Force Impulse (ARFI) technique in the evaluation of testicular tissue stiffness in vivo. MATERIALS AND METHODS:58 healthy male testes were examined using B-mode sonography and ARFI and SSI. B-mode sonograp...

journal_title：Clinical hemorheology and microcirculation

authors： Trottmann M,Rübenthaler J,Marcon J,Stief CG,Reiser MF,Clevert DA

更新日期：2016-01-01 00:00:00

abstract：:Vascular homeostasis involves endothelial function, smooth muscle function, central hemodynamics, and their interactions with blood. In this complex balance, the role of hemorheological parameters still needs to be defined, particularly with regards to its clinical implications. While the importance of microcirculatio...

journal_title：Clinical hemorheology and microcirculation

authors： Gori T

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Abdominal compartment syndrome (ACS) is a life-threatening condition, of which pathomechanism hasn't been completely clarified, yet. Furthermore, surgical therapy still needs optimization. OBJECTIVE:We aimed to investigate microcirculatory and micro-rheological alterations in ACS, using various temporary ab...

journal_title：Clinical hemorheology and microcirculation

authors： Nemeth N,Peto K,Deak A,Sogor V,Varga G,Tanczos B,Balog K,Csiszko A,Godo Z,Szentkereszty Z

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:Real-time shear-wave elastography (SWE) is a newly developed technique for the sonographic quantification of tissue elasticity, which already is used in the assessment of breast and thyroid lesions. Due to limited overlying tissue, the testes are ideally suited for assessment using shear wave elastography. To o...

journal_title：Clinical hemorheology and microcirculation

authors： Trottmann M,Marcon J,D'Anastasi M,Bruce MF,Stief CG,Reiser MF,Buchner A,Clevert DA

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:The reconstruction of metacarpal- and interphalangeal joints after severe hand injuries has been proven to be challenging. Commonly used procedures like arthrodesis, amputation or ray resection of the finger compromise the functionality of the injured finger. Especially for young patients, the restoration of...

journal_title：Clinical hemorheology and microcirculation

authors： Bachleitner K,Blank B,Klein S,Geis S,Aung T,Prantl L,Dolderer JH

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:To compare the sensitivity and specificity of contrast-enhanced ultrasound (CEUS) and computed tomography (CT) in the diagnosis of vascular complications after liver transplantation in the postoperative phase. MATERIALS AND METHODS:A total of 60 patients with elevated liver function tests after liver transplan...

journal_title：Clinical hemorheology and microcirculation

authors： Rübenthaler J,Paprottka KJ,Hameister E,Hoffmann K,Joiko N,Reiser M,Clevert DA

更新日期：2016-01-01 00:00:00

abstract：:Current haemodialysis techniques are not capable to remove efficiently low molecular weight hydrophobic uremic toxins from the blood of patients suffering from chronic renal failure. With respect to the hydrophobic characteristics and the high level of protein binding of these uremic toxins, hydrophobic adsorber mater...

journal_title：Clinical hemorheology and microcirculation

authors： Kumar RK,Basu S,Lemke HD,Jankowski J,Kratz K,Lendlein A,Tetali SD

更新日期：2016-01-01 00:00:00

abstract：:Inhalation of 100% oxygen in a hyperbaric chamber has been accepted as a useful treatment for patients with various pathologies who suffer from hypoxia. The oxidative effects of hyperbaric oxygen (HBO) on RBCs have been investigated in animals but there is not enough data on hemorheological parameters in patients foll...

journal_title：Clinical hemorheology and microcirculation

authors： Sinan M,Ertan NZ,Mirasoglu B,Yalcin O,Atac N,Toklu AS,Basaran-Kucukgergin C,Baskurt OK

更新日期：2016-01-01 00:00:00

abstract：:Accumulated uremic toxins like indoxyl sulphate, hippuric acid and p-cresyl sulphates in renal failure patients stimulate proinflammatory effects, and consequently kidney and cardiovascular diseases. Low clearance rate of these uremic toxins from the blood of uremic patients by conventional techniques like hemodialysi...

journal_title：Clinical hemorheology and microcirculation

authors： Kumar RK,Basu S,Lemke HD,Jankowski J,Kratz K,Lendlein A,Tetali SD

更新日期：2016-01-01 00:00:00

abstract：:Clinical application of platelet-rich plasma (PRP) and stem cells has become more and more important in regenerative medicine during the last decade. However, differences in PRP preparations may contribute to variable PRP compositions with unpredictable effects on a cellular level. In the present study, we modified th...

journal_title：Clinical hemorheology and microcirculation

authors： Loibl M,Lang S,Brockhoff G,Gueorguiev B,Hilber F,Worlicek M,Baumann F,Grechenig S,Zellner J,Huber M,Valderrabano V,Angele P,Nerlich M,Prantl L,Gehmert S

更新日期：2016-01-01 00:00:00

abstract：:Excessive time for analysis may impede microcirculatory studies with large amounts of video data. Engaging more personnel in the analyses seems to be a rational approach in that scenario and could shorten the time-interval between capturing images and obtaining results. Our hypothesis was that novice users would be ab...

journal_title：Clinical hemorheology and microcirculation

authors： Cerny V,Abdo I,George RB,Maddison L,Sharawi N,Lehmann C

更新日期：2016-01-01 00:00:00

abstract：:Shear stress is known to induce platelet activation and aggregation. The red blood cell (RBC) aggregation test requires the application of shear stress for the cells to disaggregate for initialization. We tested the hypothesis that applying shear stress may activate platelets, which can influence RBC aggregation. The ...

journal_title：Clinical hemorheology and microcirculation

authors： Kim JH,Lee H,Lee BK,Shin S

更新日期：2016-01-01 00:00:00

abstract：:Red blood cell (RBC) deformability is severely decreased in patients with sickle cell anemia (SCA), which plays a role in the pathophysiology of the disease. However, investigation of RBC deformability from SCA patients demands careful methodological considerations. We assessed RBC deformability by ektacytometry (LORR...

journal_title：Clinical hemorheology and microcirculation

authors： Renoux C,Parrow N,Faes C,Joly P,Hardeman M,Tisdale J,Levine M,Garnier N,Bertrand Y,Kebaili K,Cuzzubbo D,Cannas G,Martin C,Connes P

更新日期：2016-01-01 00:00:00

abstract：:Determination of shear stresses at given shear rates allow approximation of flow curves by mathematical models and to calculate viscosities of non-Newtonian fluids. In term neonates, the mean arterial blood pressure (MAP) is markedly below that of adults, therefore rheological properties of blood play an important rol...

journal_title：Clinical hemorheology and microcirculation

authors： Kuss N,Bauknecht E,Felbinger C,Gehm J,Gehm L,Pöschl J,Ruef P

更新日期：2015-10-06 00:00:00

abstract：BACKGROUND:Renal failure is a disease with accelerated atherosclerosis beginning with endothelial cell dysfunction. Factors affecting endothelial cell dysfunction include whole blood viscosity (WBV) and asymmetric dimethylarginine (ADMA). The relationship in controls and renal failure was determined. METHODS:51 subjec...

journal_title：Clinical hemorheology and microcirculation

authors： Hammes MS,Watson S,Coe FL,Ahmed F,Beltran E,Dhar P

更新日期：2015-01-01 00:00:00

abstract：:Increased RDW has been found to be a marker of adverse outcomes in cardiovascular disease (CVD), although the exact mechanism remains unclear. Recently, several authors have found that higher RDW is associated with decreased erythrocyte deformability, which can impair blood flow through microcirculation, a fact which ...

journal_title：Clinical hemorheology and microcirculation

authors： Vayá A,Rivera L,de la Espriella R,Sanchez F,Suescun M,Hernandez JL,Fácila L

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Advances in rapid-prototyping and 3D printing technologies have enhanced the possibilities in preparing designed architectures for tissue engineering applications. A major advantage in custom designing is the ability to create structures with desired mechanical properties. While the behaviour of a designed s...

journal_title：Clinical hemorheology and microcirculation

authors： Narra N,Blanquer SB,Haimi SP,Grijpma DW,Hyttinen J

更新日期：2015-01-01 00:00:00